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    T cell

    One type of white blood cell that attacks virus-infected cells, foreign cells, and cancer cells. T cells also produce a number of substances that regulate the immune response. (National Cancer Institute)



    AustCancer Completes Patient Recruitment for Phase IIb Pentrys ... 17 Mar 2005
    ...in the trial, assays will be performed on blood samples to detect antibodies against p53, antibodies against Pentrys(TM), and T cell responses against p53. ... Business Wire (press release),

    A new role for leptin as a direct satiety signal from the stomach 17 Mar 2005
    C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, and O’Rahilly S. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and ... AJP-Regul Integr Comp Physiology (subscription)

    KineMed Announces Award of SBIR Phase I Grant for Program in ... 17 Mar 2005
    Pathologically, MS is characterized by the presence of areas of demyelination and T-cell predominant perivascular inflammation in the brain white matter. ... Yahoo News (press release)

    Pregnancy and Other Factors Associated With Higher CD4+ T-Cell ... Mar 15, 2005
    Patients were included in the analysis if they had a CD4+ T-cell count recorded within 6 months of their first positive HIV test ( N = 1858). ... Medscape (subscription)

    Heterologous T cell immunity in severe hepatitis C virus infection Mar 7, 2005
    To determine whether this mechanism can influence the course of HCV infection, we analyzed the features of the HCV-specific CD8 T cell response in eight ... Journal of Experimental Medicine

    Earlier use of prostate cancer vaccines urged by Hopkins ... Mar 16, 2005
    ...destruction. Changes in proteins on the T-cell's surface give clues to whether they "see" the cancer and are targeting it. Those ... Medical News Today,

    BioCryst Pharmaceuticals Successfully Completes Phase I Trial With ... Mar 15, 2005
    ...dose- related inhibition of PNP, which effectively increases the serum level of deoxyguanosine that is necessary for selective suppression of T-cell activation ... PR Newswire (press release)

    Don't cell them short: Why some reject the wireless wave Feb 17, 2005
    Journey with us now as we search for that most endangered of species, the Cell-Phone Luddite. For the uninitiated, CPLs may be hard ... AZ Central.com,

    T cell receptor engagement by peptide–MHC ligands induces a ... Feb 22, 2005
    The T cell receptor (TCR) can recognize a variety of cognate peptide/major histocompatibility complex (pMHC) ligands and translate their affinity into distinct ... Journal of Experimental Medicine

    LIAI Scientists Make Important Finding on Regulation of Immune ... Mar 3, 2005
    In a paper, "CD4+ T-cell help regulates CD8+ T-cell memory via TRAIL-mediated activation-induced cell death," published today in the scientific journal Nature ... PharmaLive.com (press release),

    Favrille, Inc. Reports Fourth Quarter and Year End 2004 Financial ... Mar 14, 2005
    ...aggressive form of lymphoma. -- A Phase I/II trial of our product candidate FAV-201 in patients with T-cell NHL. We expect total ... Yahoo News (press release)

    Epimmune and IDM Agree to Combine Businesses Mar 16, 2005
    Epitopes, critical signaling molecules, stimulate the T cell arm of the immune system to respond to specific regions of cancer cells or infectious agents. ... Yahoo News (press release)

    Private aspects of heterologous immunity Mar 7, 2005
    New studies now show that each subject's history of past infections individualizes the memory T cell pool. Private T cell receptor ... Journal of Experimental Medicine

    A moment with... Clay Siegall, President and CEO of Seattle ... Mar 14, 2005
    One is for lung cancer. The other is for multiple myeloma and lymphoma. The third one is for Hodgkin's disease and T-cell lymphoma. ... Seattle Post Intelligencer

    Signal-joint TRECs might predict success of stem cell transplant Feb 25, 2005
    ...predict whether children receiving such a transplant will experience either failure or significant delay in the reconstitution of the T cell population. ... RxPG NEWS,

    Epidermal Differentiation: The Role of Proteases and Their ... Feb 27, 2005
    ...mice have revealed that cathepsin C plays an essential role in processing and activation of granzymes A and B, which are required for T-cell-mediated cell ... RedNova.com,

    Researchers find possible breast cancer cure Mar 15, 2005
    ...protein. "The T cell comes in and identifies the target cells [which causes them to] lyse (or self-destruct)," said Narayanan. Specialized ... Student Life,

    Avidex yields immunotherapeutic protein platform Mar 3, 2005
    03/03/2005 - Avidex has announced the publication of data that demonstrates the potential of new immunotherapeutics based on the T cell immune response, which ... Drug Researcher.com,

    Geron Announces Publication of Phase 1-2 Telomerase Vaccine Study ... Mar 4, 2005
    The results show that the vaccination protocol successfully generated telomerase-specific T-cell responses in 19 of 20 subjects. ... Business Wire (press release),

    Archives: The following articles may no longer be available on the web. If you want to inquire on a particular article, please contact the source publication (listed in parentheses).




    Don't cell out on safety May 23, 2004
    BY MICHAEL VIRTANEN. ORTH ELBA, NY -- When rangers hiked up New York's highest mountain on a recent rescue, they were answering a cell phone call from the peak. ... Chicago Sun Times

    Endogenous Presentation of CD8 + T Cell Epitopes from Epstein- ...  May 17, 2004
    Furthermore, we show that EBV-infected B cells can readily activate EBNA1-specific memory T cell responses from healthy virus carriers. ... Journal of Experimental Medicine - May 17, 2004
    ... Furthermore, we show that EBV-infected B cells can readily activate EBNA1-specific memory T cell responses from healthy virus carriers. ...

    CD8 T Cell Recognition of Endogenously Expressed Epstein-Barr ... Journal of Experimental Medicine - May 17, 2004
    ... Here, using CD8 + T cell clones to native EBNA1 epitopes upstream and downstream of the GAr domain and assaying recognition by interferon release, we show that ...
    Epstein-Barr Virus Nuclear Antigen 1Journal of Experimental Medicine - May 17, 2004
    ... EBNA1 contains a Gly-Ala repeat domain which was found to prevent antigen processing for cytolytic CD8 + T cell recognition (9). Presence of this Gly-Ala ...
    Prednisolone delays CD4 T-cell decreases in chronic HIV infectionAidsmap

    CD8 T Cell Recognition of Endogenously Expressed Epstein-Barr ...  May 17, 2004
    Here, using CD8 + T cell clones to native EBNA1 epitopes upstream and downstream of the GAr domain and assaying recognition by interferon release, we show that ... Journal of Experimental Medicine - May 17, 2004
    ... Here, using CD8 + T cell clones to native EBNA1 epitopes upstream and downstream of the GAr domain and assaying recognition by interferon release, we show that ...

    Epstein-Barr Virus Nuclear Antigen 1Journal of Experimental Medicine - May 17, 2004
    ... EBNA1 contains a Gly-Ala repeat domain which was found to prevent antigen processing for cytolytic CD8 + T cell recognition (9). Presence of this Gly-Ala ...
    Prednisolone delays CD4 T-cell decreases in chronic HIV infectionAidsmap

    Epstein-Barr Virus Nuclear Antigen 1 May 17, 2004
    EBNA1 contains a Gly-Ala repeat domain which was found to prevent antigen processing for cytolytic CD8 + T cell recognition (9). Presence of this Gly-Ala ... Journal of Experimental Medicine - May 17, 2004
    ... EBNA1 contains a Gly-Ala repeat domain which was found to prevent antigen processing for cytolytic CD8 + T cell recognition (9). Presence of this Gly-Ala ...

    Prednisolone delays CD4 T-cell decreases in chronic HIV infectionAidsmap

    Prednisolone delays CD4 T-cell decreases in chronic HIV infection May 6, 2004
    The observed effects on CD4 counts in the prednisolone-treated patients were mirrored by decreases in the presence of markers of T-cell death (apoptosis) and ... Aidsmap

    Understanding T-cell memory Apr 23, 2004
    Researchers report in the in the April 23 Science that the reason some T cells survive the T-cell die-off following infection clearance—and therefore provide ... Biomedcentral.com

    The Cell Surface Receptor SLAM Controls T Cell and Macrophage ...  May 3, 2004
    ...a glycoprotein expressed on activated lymphocytes and antigen-presenting cells, has been shown to be a coregulator of antigen-driven T cell responses and is ... Journal of Experimental Medicine - May 3, 2004
    ... a glycoprotein expressed on activated lymphocytes and antigen-presenting cells, has been shown to be a coregulator of antigen-driven T cell responses and is ...

    Health India > Scientists identify protein linked to auto-immune ... New Kerala

    Health India > Scientists identify protein linked to auto-immune ...  May 20, 2004
    Scientists at four medical research institutes have reportedly identified a protein that can regulate immune or T-cell functioning to contribute to the ... New Kerala

    Tissue, Cell Donors Screened Under New US Rule May 20, 2004
    These include the incurable brain-wasting Creutzfeldt-Jakob disease, syphilis and, for relevant tissues, human T-cell lymphotropic virus or HTLV, which is ... Reuters - May 20, 2004
    ... These include the incurable brain-wasting Creutzfeldt-Jakob disease, syphilis and, for relevant tissues, human T-cell lymphotropic virus or HTLV, which is ...

    State can't pay for HIV, AIDS drugs for 115Kentucky.com

    State can't pay for HIV, AIDS drugs for 115 May 20, 2004
    ...$10,000 and have no insurance or Medicaid coverage. He or she must also have medical documentation of CD4 T-cell count and viral load. Kentucky.com

    Protein may reduce susceptibility to autoimmune disease May 18, 2004
    ...associated antigen-4 (CTLA-4) is well known as an important regulator of the immune system and plays a critical role in down-regulating T cell responses. ... EurekAlert

    Tissue, Cell Donors Screened Under New Rule May 20, 2004
    These include the incurable brain-wasting Creutzfeldt-Jakob disease (news - web sites), syphilis and, for relevant tissues, human T-cell lymphotropic virus or ... Yahoo News - May 20, 2004
    ... These include the incurable brain-wasting Creutzfeldt-Jakob disease (news - web sites), syphilis and, for relevant tissues, human T-cell lymphotropic virus or ...

    Family Alleges Mistaken Medicine Caused Man's DeathKMBC

    Family Alleges Mistaken Medicine Caused Man's Death May 21, 2004
    But the couple's first trial came as quick as their courtship. In the spring of 2003, Matt was diagnosed with T-cell lymphoma. Cancer. ... KMBC

    Norwood Immunology Limited Announces the Appointment of Rolf ...  May 21, 2004
    ...use of GnRH analogues to boost the immune system, through regrowth of the thymus, improvements in bone marrow function and enhancement of T cell functionality. ... Business Wire (press release)

    Weekly cycles of once-daily anti-HIV drugs could reduce cost of ...  May 20, 2004
    During this period, the study volunteers had no significant changes in their CD4+ T-cell counts, and no evidence of resistance to the antiretroviral drugs in ... EurekAlert

    PowderMed Launched in Spin Out of Powder Injection DNA Vaccine ...  May 16, 2004
    ...gold and becomes transcriptionally active, producing the encoded protein that when presented by the APCs to lymphocytes, triggers strong T-cell mediated immune ... Yahoo News (press release) - May 16, 2004
    ... gold and becomes transcriptionally active, producing the encoded protein that when presented by the APCs to lymphocytes, triggers strong T-cell mediated immune ...

    PowderJect renewed in Chiron spin-outIn Pharma

    PowderJect renewed in Chiron spin-out May 17, 2004
    The technology stimulates a powerful T-cell mediated immune response to a broad range of viral and cancer antigens, and the strength of this response is what ... In Pharma

    NIH Launches Study Of Hematopoietic Stem Cell Transplantation For ...  May 18, 2004
    ...lupus. B cell studies will be conducted by scientists at NIAMS, while T cell studies will be conducted by scientists at NCI. Researchers ... Science Daily (press release) - May 18, 2004
    ... lupus. B cell studies will be conducted by scientists at NIAMS, while T cell studies will be conducted by scientists at NCI. Researchers ...

    Genmab Announces Positive HuMax-CD4 Phase II Lymphoma DataYahoo News (press release) - Apr 28, 2004
    ... that 55% of higher dose patients in the primary indication (10/18) achieved at least a partial response in HuMax-CD4 Phase II cutaneous T-cell lymphoma (CTCL ...
    Blood drive to benefit boy, 2, with leukemiaOrange Leader

    Genmab Announces Positive HuMax-CD4 Phase II Lymphoma Data Apr 28, 2004
    ...that 55% of higher dose patients in the primary indication (10/18) achieved at least a partial response in HuMax-CD4 Phase II cutaneous T-cell lymphoma (CTCL ... Yahoo News (press release) - Apr 28, 2004
    ... that 55% of higher dose patients in the primary indication (10/18) achieved at least a partial response in HuMax-CD4 Phase II cutaneous T-cell lymphoma (CTCL ...

    Blood drive to benefit boy, 2, with leukemiaOrange Leader

    Blood drive to benefit boy, 2, with leukemia May 16, 2004
    Trace's bald head is a reminder of what the family has been through and still has to go through since the boy was diagnosed with T-cell acute lymphocytic ... Orange Leader


    Resources from the National Cancer Institute on T cell:



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